Article
Assessing tumor mutations to gain insight into base excision repair sequence polymorphisms and smoking in colon cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2009
Curtin Karen, Samowitz Wade S, Wolff Roger K, Ulrich Cornelia M, Caan Bette J, Potter John D, Slattery Martha L
Abstract excerpt
DNA repair enzymes function in major pathways to reverse DNA damage, including base excision repair (BER). Missense polymorphisms in BER repair genes may contribute to differences in DNA repair capacity, specific mutations, and susceptibility to cancer in the presence of exposure to carcinogens s...
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