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Article

A population-based case-control study of the XRCC1 Arg399Gln polymorphism and susceptibility to bladder cancer.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Aug 2004

Kelsey Karl T, Park Sunyeong, Nelson Heather H, Karagas Margaret R

Abstract excerpt

Cigarette smoking is the major cause of bladder cancer. Constituents in tobacco smoke can induce oxidative DNA damage requiring base excision repair. The Arg399Gln polymorphism in the DNA base excision repair gene XRCC1 is associated with several phenotypic markers of reduced DNA repair capacity. Results from several epidemiologic studies suggest that the Arg399Gln polymorphism may influence susceptibility to...

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Identifiers

PMID: 15298955

Genes

XRCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A population-based case-control study of the XRCC1 Arg399Gln polymorphism and susceptibility to bladder cancer.PMID 15298955Read ↗

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Association of XRCC1 Arg399Gln polymorphism with bladder cancer susceptibility: a meta-analysis.Semantic proximity Read ↗

DNA repair gene XRCC1 polymorphisms and bladder cancer risk.Semantic proximity Read ↗

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