Article
Comparative study of the gating motif and C-type inactivation in prokaryotic voltage-gated sodium channels.
The Journal of biological chemistry - 5 Feb 2010
Irie Katsumasa, Kitagawa Kazuya, Nagura Hitoshi, Imai Tomoya, Shimomura Takushi, Fujiyoshi Yoshinori
Abstract excerpt
Prokaryotic voltage-gated sodium channels (Na(V)s) are homotetramers and are thought to inactivate through a single mechanism, named C-type inactivation. Here we report the voltage dependence and inactivation rate of the NaChBac channel from Bacillus halodurans, the first identified prokaryotic Na(V), as well as of three new homologues cloned from Bacillus licheniformis (Na(V)BacL), Shewanella putrefaciens...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
