Article
Yeast RAS2 mutations modulating the ras-guanine exchange factor interaction.
FEBS letters - 10 Feb 1997
Hermann-Le Denmat S, Jacquet M
Abstract excerpt
We have used a two-hybrid approach to test various forms of Saccharomyces cerevisiae Ras2p for their ability to interact with the human guanine nucleotide exchange factor HGRF55. We have previously shown that a strong two-hybrid interaction is found between the HGRF55p and the dominant negative R...
Topics
- Alleles
- Binding Sites
- Fungal Proteins
- Genetic Complementation Test
- Guanine Nucleotide Exchange Factors
- Humans
- Hybrid Cells
- Mutation
- Promoter Regions, Genetic
- Protein Conformation
- Proteins
- Recombinant Fusion Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- beta-Galactosidase
- ras Guanine Nucleotide Exchange Factors
- ras Proteins