The vaccinia virus A18R protein plays a role in viral transcription during both the early and the late phases of infection.

doi:10.1128/JVI.68.6.3642-3649.1994

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Article

The vaccinia virus A18R protein plays a role in viral transcription during both the early and the late phases of infection.

Journal of virology - 1 Jun 1994

Simpson D A, Condit R C

Abstract excerpt

The vaccinia virus gene A18R is essential for virus infection. The loss of A18R protein function results in unregulated transcription late during virus infection from regions of the viral genome which are normally transcriptionally quiescent. We have characterized A18R protein expression in cells...

Topics

Cell Line
Genes, Viral
Humans
Mutation
Temperature
Transcription, Genetic
Vaccinia
Vaccinia virus
Viral Proteins

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