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Article

A naturally occurring human RPA subunit homolog does not support DNA replication or cell-cycle progression.

Nucleic acids research - 1 Jan 2010

Haring Stuart J, Humphreys Troy D, Wold Marc S

Abstract excerpt

Replication Protein A (RPA) is a single-stranded DNA-binding protein essential for DNA replication, repair, recombination and cell-cycle regulation. A human homolog of the RPA2 subunit, called RPA4, was previously identified and shown to be expressed in colon mucosal and placental cells; however, the function of RPA4 was not determined. To examine the function of RPA4 in human cells, we carried out knockdown and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19942684
DOI: 10.1093/nar/gkp1062
PMCID: PMC2817474

Genes

RPA4
RPA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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