Article
p53 genotype predicts response to chemotherapy in patients with squamous cell carcinoma of the esophagus.
Annals of surgical oncology - 1 Feb 2010
Yamasaki Makoto, Miyata Hiroshi, Fujiwara Yoshiyuki, Takiguchi Shuji, Nakajima Kiyokazu, Nishida Toshirou, Yasuda Takushi, Matsuyama Jin, Mori Masaki, Doki Yuichiro
Abstract excerpt
BACKGROUND: Response to chemotherapy and anatomical spread are significant prognostic factors in patients with esophageal squamous cell carcinoma (ESCC) treated by chemotherapy then surgery. Predicting the response to chemotherapy would allow significant optimization of cancer treatment. METHODS: Genomic mutation and protein expression of p53 were investigated retrospectively by polymerase chain reaction (PCR)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
