Article
p53 sequence analysis predicts treatment response and outcome of patients with esophageal carcinoma.
Cancer - 1 Jul 1998
Ribeiro U, Finkelstein S D, Safatle-Ribeiro A V, Landreneau R J, Clarke M R, Bakker A, Swalsky P A, Gooding W E, Posner M C
Abstract excerpt
BACKGROUND: The ability to predict biologic behavior and treatment responsiveness would be a valuable asset in the multimodality approach to esophageal carcinoma. The authors examined whether alterations of the p53 gene correlate with clinicopathologic parameters, response to preoperative chemoth...
Topics
- Adult
- Aged
- Esophageal Neoplasms
- Female
- Genes, p53
- Genotype
- Humans
- Immunohistochemistry
- Male
- Middle Aged
- Point Mutation
- Prognosis
- Treatment Outcome
- Tumor Suppressor Protein p53
