Growing clinical evidence for the interaction of the p53 genotype and response to induction chemotherapy in advanced non-small cell lung cancer.

doi:10.1016/j.jtcvs.2007.10.072

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Article

Growing clinical evidence for the interaction of the p53 genotype and response to induction chemotherapy in advanced non-small cell lung cancer.

The Journal of thoracic and cardiovascular surgery - 1 May 2008

Kandioler Daniela, Stamatis Georgios, Eberhardt Wilfried, Kappel Sonja, Zöchbauer-Müller Sabine, Kührer Irene, Mittlböck Martina, Zwrtek Ronald, Aigner Clemens, Bichler Christoph, Tichy Victoria, Hudec Marcus, Bachleitner Thomas, End Adelheid, Müller Michael Rolf, Roth Erich, Klepetko Walter

Abstract excerpt

OBJECTIVE: The objective of this study is to establish clinical evidence that the p53 genotype can serve as a predictive marker for response to cisplatin-based induction therapy. METHODS: Patients with advanced non-small cell lung cancer who had received neoadjuvant chemotherapy in the context of a prospective phase II trial were analyzed for the p53 genotype of their tumors. Response to induction therapy was...

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PMID: 18455581
DOI: 10.1016/j.jtcvs.2007.10.072

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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