Article
The nuclear receptor PXR gene variants are associated with liver injury in nonalcoholic fatty liver disease.
Pharmacogenetics and genomics - 1 Jan 2010
Sookoian Silvia, Castaño Gustavo O, Burgueño Adriana L, Gianotti Tomas Fernández, Rosselli María Soledad, Pirola Carlos Jose
Abstract excerpt
OBJECTIVE: To explore the contribution of gene variants and derived haplotypes of the pregnane X receptor (NR1I2) to the severity of nonalcoholic fatty liver disease (NAFLD). METHODS: A total of 290 individuals were evaluated in a case-control association study, including 188 NAFLD patients with...
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