Combined effects of PNPLA3, TM6SF2 and HSD17B13 variants on severity of biopsy-proven non-alcoholic fatty liver disease.

doi:10.1007/s12072-021-10200-y

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Combined effects of PNPLA3, TM6SF2 and HSD17B13 variants on severity of biopsy-proven non-alcoholic fatty liver disease.

Hepatology international - 1 Aug 2021

Paternostro Rafael, Staufer Katharina, Traussnigg Stefan, Stättermayer Albert-Friedrich, Halilbasic Emina, Keritam Omar, Meyer Elias L, Stift Judith, Wrba Fritz, Sipos Bence, Canbay Ali, Schlattjan Martin, Aigner Elmar, Datz Christian, Stickel Felix, Schafmayer Clemens, Hampe Jochen, Buch Stephan, Prager Gerhard, Munda Petra, Mandorfer Mattias, Ferenci Peter, Trauner Michael

Abstract excerpt

OBJECTIVE: Several single-nucleotide polymorphisms have been identified to be disadvantageous or protective in regard to disease severity in patients with non-alcoholic fatty liver disease (NAFLD). However, it is unclear, whether including genetic risk factor(s) either alone or combined into risk stratification algorithms for NAFLD actually provides incremental benefit over clinical risk factors. DESIGN: Patients...

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PMID: 34076851
DOI: 10.1007/s12072-021-10200-y
PMCID: PMC8382644

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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