Article
Nonalcoholic fatty liver disease risk and histologic severity are associated with genetic polymorphisms in children.
Hepatology (Baltimore, Md.) - 1 Jan 2023
Goyal Nidhi P, Rosenthal Sara B, Nasamran Chanod, Behling Cynthia A, Angeles Jorge E, Fishbein Mark H, Harlow Kathryn E, Jain Ajay K, Molleston Jean P, Newton Kimberly P, Ugalde-Nicalo Patricia, Xanthankos Stavra A, Yates Katherine, Schork Nicholas J, Fisch Kathleen M, Schwimmer Jeffrey B
Abstract excerpt
BACKGROUND AND AIMS: NAFLD is the most common chronic liver disease in children. Large pediatric studies identifying single nucleotide polymorphisms (SNPs) associated with risk and histologic severity of NAFLD are limited. Study aims included investigating SNPs associated with risk for NAFLD using family trios and association of candidate alleles with histologic severity. APPROACH AND RESULTS: Children with...
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