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Article

Transgenic mice with a constitutively active aryl hydrocarbon receptor display a gender-specific bone phenotype.

Toxicological sciences : an official journal of the Society of Toxicology - 1 Mar 2010

Wejheden Carolina, Brunnberg Sara, Larsson Sune, Lind P Monica, Lind Pia M, Andersson Göran, Hanberg Annika

Abstract excerpt

Bone tissue homeostasis is governed by hormones, growth factors, and cytokines and can be distorted by environmental pollutants, such as ligands to the aryl hydrocarbon receptor (AhR). A transgenic mouse expressing a constitutively active aryl hydrocarbon receptor (CA-AhR), mimicking continuous low-dose exposure to AhR ligands, was used to explore potential long-term effects of these ligands on bone. The density,...

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PMID: 19934163
DOI: 10.1093/toxsci/kfp284

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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