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Article

Circadian Clock Regulates Bone Resorption in Mice

3 Feb 2016

Abstract excerpt

The circadian clock controls many behavioral and physiological processes beyond daily rhythms. Circadian dysfunction increases the risk of cancer, obesity, and cardiovascular and metabolic diseases. Although clinical studies have shown that bone resorption is controlled by circadian rhythm, as indicated by diurnal variations in bone resorption, the molecular mechanism of circadian clock-dependent bone resorption...

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PMID: 26841172
DOI: 10.1002/jbmr.2803

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