Article
Prostate phenotypes in estrogen-modulated transgenic mice.
Trends in endocrinology and metabolism: TEM - 1 Jan 2000
Jarred Renea A, McPherson Stephen J, Bianco Joseph J, Couse John F, Korach Kenneth S, Risbridger Gail P
Abstract excerpt
Estrogen-modulated transgenic mice, such as estrogen receptor-knockouts (alphaERKO and betaERKO), aromatase-knockout (ArKO) and aromatase-overexpressing (AROM+) mice, have contributed to our understanding of the roles of estrogens in male reproductive biology, including prostate growth and development. Varying pathological changes of the prostate have been described as being the result of aberrant actions of...
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