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Article

New insights to the role of aryl hydrocarbon receptor in bone phenotype and in dioxin-induced modulation of bone microarchitecture and material properties.

Toxicology and applied pharmacology - 15 Nov 2013

Herlin Maria, Finnilä Mikko A J, Zioupos Peter, Aula Antti, Risteli Juha, Miettinen Hanna M, Jämsä Timo, Tuukkanen Juha, Korkalainen Merja, Håkansson Helen, Viluksela Matti

Abstract excerpt

Bone is a target for high affinity aryl hydrocarbon receptor (AHR) ligands, such as dioxins. Although bone morphology, mineral density and strength are sensitive endpoints of dioxin toxicity, less is known about effects on bone microarchitecture and material properties. This study characterizes TCDD-induced modulations of bone tissue, and the role of AHR in dioxin-induced bone toxicity and for normal bone...

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Source

Identifiers

PMID: 24035824
DOI: 10.1016/j.taap.2013.09.002

Genes

AHR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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