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Article

Effect of tamoxifen on cell lines displaying the multidrug-resistant phenotype.

Blood - 15 Feb 1991

Berman E, Adams M, Duigou-Osterndorf R, Godfrey L, Clarkson B, Andreeff M

Abstract excerpt

We examined the effect of tamoxifen (Tmx), verapamil, and daunorubicin (DNR) in two cell lines that displayed the multidrug-resistant (MDR) phenotype and used laser flow cytometry to quantitate intracellular DNR content. In the vinblastine-resistant human lymphoblastic lymphoma cell line CEM-VBL, simultaneous incubation of DNR with Tmx 10 mumol/L or Tmx 50 mumol/L increased intracellular DNR fluorescence in a...

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PMID: 1993221

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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