Article
Effect of tamoxifen on cell lines displaying the multidrug-resistant phenotype.
Blood - 15 Feb 1991
Berman E, Adams M, Duigou-Osterndorf R, Godfrey L, Clarkson B, Andreeff M
Abstract excerpt
We examined the effect of tamoxifen (Tmx), verapamil, and daunorubicin (DNR) in two cell lines that displayed the multidrug-resistant (MDR) phenotype and used laser flow cytometry to quantitate intracellular DNR content. In the vinblastine-resistant human lymphoblastic lymphoma cell line CEM-VBL,...
Topics
- Cell Division
- Daunorubicin
- Drug Resistance
- Flow Cytometry
- Humans
- Kinetics
- Leukemia, Lymphoid
- Leukemia, Myeloid, Acute
- Phenotype
- Tamoxifen
- Tumor Cells, Cultured
- Verapamil
- Vinblastine