Retention of vital dyes correlates inversely with the multidrug-resistant phenotype of adriamycin-selected murine fibrosarcoma variants.

doi:10.1016/0014-4827(90)90145-z

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Article

Retention of vital dyes correlates inversely with the multidrug-resistant phenotype of adriamycin-selected murine fibrosarcoma variants.

Experimental cell research - 1 Sept 1990

Bucana C D, Giavazzi R, Nayar R, O'Brian C A, Seid C, Earnest L E, Fan D

Abstract excerpt

Retention of the vital dyes rhodamine 123 (R-123) and hydroethidine (HET) correlates inversely with the multidrug resistant phenotypes of the adriamycin (ADM)-selected variants of a uv-induced murine fibrosarcoma cell line (UV-2237M). The differential affinity of these dyes for specific cellular...

Topics

Animals
Calcium
Coloring Agents
Doxorubicin
Drug Resistance
Ethidium
Fibrosarcoma
Mice
Phenanthridines
Phenotype
Rhodamine 123
Rhodamines
Tumor Cells, Cultured

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