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Article

Integrative genomics identifies DSCR1 (RCAN1) as a novel NFAT-dependent mediator of phenotypic modulation in vascular smooth muscle cells

19 Nov 2009

Abstract excerpt

Vascular smooth muscle cells (SMCs) display remarkable phenotypic plasticity in response to environmental cues. The nuclear factor of activated T-cells (NFAT) family of transcription factors plays a critical role in vascular pathology. However, known functional NFAT gene targets in vascular SMCs are currently limited. Publicly available whole-genome expression array data sets were analyzed to identify...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 19926569
DOI: 10.1093/hmg/ddp511

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