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Article

Nuclear factor of activated T cells 5 regulates vascular smooth muscle cell phenotypic modulation.

Arteriosclerosis, thrombosis, and vascular biology - 1 Oct 2011

Halterman Julia A, Kwon H Moo, Zargham Ramin, Bortz Pamela D Schoppee, Wamhoff Brian R

Abstract excerpt

OBJECTIVE: The tonicity-responsive transcription factor, nuclear factor of activated T cells 5 (NFAT5/tonicity enhancer binding protein [TonEBP]), has been well characterized in numerous cell types; however, NFAT5 function in vascular smooth muscle cells (SMCs) is unknown. Our main objective was to determine the role of NFAT5 regulation in SMCs. METHODS AND RESULTS: We showed that NFAT5 is regulated by...

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Identifiers

PMID: 21757659
DOI: 10.1161/ATVBAHA.111.232165
PMCID: PMC3188807

Genes

NFAT5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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