Article
The implication of CNR1 gene's polymorphisms in the modulation of endocannabinoid system effects.
Romanian journal of internal medicine = Revue roumaine de medecine interne - 1 Jan 2009
Dinu I R, Popa Simona, Bîcu Mihaela, Moţa E, Moţa Maria
Abstract excerpt
The endocannabinoid system (ECS) represents one of the most important physiologic systems involved in organism homeostasis, having various implications upon individual behavior and metabolic phenotype. It is composed of cannabinoid receptors CB1 and CB2, and their genes (CNR1 and CNR2), their endogenous ligands and the enzymes which mediate endogenous ligands' biosynthesis and degradation. Anandamide and...
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