Article
Circulating Endocannabinoids and the Polymorphism 385C>A in Fatty Acid Amide Hydrolase (FAAH) Gene May Identify the Obesity Phenotype Related to Cardiometabolic Risk: A Study Conducted in a Brazilian Population of Complex Interethnic Admixture.
PloS one - 1 Jan 2015
Martins Cyro José de Moraes, Genelhu Virginia, Pimentel Marcia Mattos Gonçalves, Celoria Bruno Miguel Jorge, Mangia Rogerio Fabris, Aveta Teresa, Silvestri Cristoforo, Di Marzo Vincenzo, Francischetti Emilio Antonio
Abstract excerpt
The dysregulation of the endocannabinoid system is associated with cardiometabolic complications of obesity. Allelic variants in coding genes for this system components may contribute to differences in the susceptibility to obesity and related health hazards. These data have mostly been shown in Caucasian populations and in severely obese individuals. We investigated a multiethnic Brazilian population to study...
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