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Article

Variants in the CNR1 and the FAAH genes and adiposity traits in the community.

Obesity (Silver Spring, Md.) - 1 Apr 2009

Lieb Wolfgang, Manning Alisa K, Florez Jose C, Dupuis Josée, Cupples L Adrienne, McAteer Jarred B, Vasan Ramachandran S, Hoffmann Udo, O'Donnell Christopher J, Meigs James B, Fox Caroline S

Abstract excerpt

Pharmacologic blockade of the endocannabinoid receptor 1 leads to weight loss and an improved metabolic risk profile in overweight and obese individuals. We hypothesize that common genetic variants in the CNR1 (encoding endocannabinoid receptor 1) and FAAH genes (encoding fatty acid amide hydrolase, a key enzyme hydrolyzing endocannabinoids) are associated with adiposity traits. We genotyped 18 single-nucleotide...

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Share to Adiposity
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 19165169
DOI: 10.1038/oby.2008.608
PMCID: PMC3039277

Genes

CNR1
FAAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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