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Article

A major quantitative trait locus on mouse chromosome 3 is involved in disease susceptibility in different colitis models.

Gastroenterology - 1 Jan 2005

Borm Michelle E A, He Jianping, Kelsall Brian, Peña A Salvador, Strober Warren, Bouma Gerd

Abstract excerpt

BACKGROUND & AIMS: Mice with a disrupted gene for the G-protein alpha inhibitory 2 chain ( Gnai2 -/- ) develop a spontaneous colitis resembling human inflammatory bowel disease. Disease expression differs markedly between inbred strains of mice, indicating genetic control of disease susceptibility. We performed a genome-wide screen to localize the chromosomal regions regulating disease expression. METHODS: A...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to GTP-Binding Protein alpha Subunits, Gi-Go

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Source

Identifiers

PMID: 15633125
DOI: 10.1053/j.gastro.2004.10.044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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