Article
Identification of regulatory residues of the yeast adenylyl cyclase.
The EMBO journal - 1 Feb 1991
Feger G, De Vendittis E, Vitelli A, Masturzo P, Zahn R, Verrotti A C, Kavounis C, Pal G P, Fasano O
Abstract excerpt
We have attempted to identify amino acid residues of the yeast adenylyl cyclase that are involved in the regulation of its activity, by isolating adenylyl cyclase-linked spontaneous mutations capable of suppressing the temperature-sensitive phenotype of ras1- ras2-ts1 strains. We previously identified a mutated adenylyl cyclase in which a single point mutation, called CR14, led to the replacement of threonine...
Topics
- Adenylyl Cyclases
- Amino Acid Sequence
- Base Sequence
- Cell Membrane
- Chromosomes, Fungal
- Genes, Fungal
- Genetic Vectors
- Genotype
- Molecular Sequence Data
- Mutagenesis
- Oligonucleotide Probes