Article
Coiled-coil interaction of N-terminal 36 residues of cyclase-associated protein with adenylyl cyclase is sufficient for its function in Saccharomyces cerevisiae ras pathway.
The Journal of biological chemistry - 23 Oct 1998
Nishida Y, Shima F, Sen H, Tanaka Y, Yanagihara C, Yamawaki-Kataoka Y, Kariya K, Kataoka T
Abstract excerpt
In the budding yeast Saccharomyces cerevisiae, association with the 70-kDa cyclase-associated protein (CAP) is required for proper response of adenylyl cyclase to Ras proteins. We show here that a small segment comprising the N-terminal 36 amino acid residues of CAP is sufficient for association...
Topics
- Adaptor Proteins, Signal Transducing
- Adenylyl Cyclases
- Binding Sites
- Cell Cycle Proteins
- Cytoskeletal Proteins
- Drosophila Proteins
- Fungal Proteins
- Microfilament Proteins
- Mutation
- Peptide Fragments
- Protein Binding
- Protein Structure, Secondary
- Protein Structure, Tertiary