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Article

Prognostic relevance of DNA copy number changes in colorectal cancer

10 Oct 2009

Abstract excerpt

In a study of 109 colorectal cancers, DNA copy number aberrations were identified by comparative genomic hybridization using a DNA microarray covering the entire genome at an average interval of less than 1 Mbase. Four patterns were revealed by unsupervised clustering analysis, one of them associated with significantly better prognosis than the others. This group contained tumours with short, dispersed, and...

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PMID: 19911421
DOI: 10.1002/path.2640

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