Article
Molecular inversion probe analysis of gene copy alterations reveals distinct categories of colorectal carcinoma.
Cancer research - 15 Aug 2006
Ji Hanlee, Kumm Jochen, Zhang Michael, Farnam Kyle, Salari Keyan, Faham Malek, Ford James M, Davis Ronald W
Abstract excerpt
Genomic instability is a major feature of neoplastic development in colorectal carcinoma and other cancers. Specific genomic instability events, such as deletions in chromosomes and other alterations in gene copy number, have potential utility as biologically relevant prognostic biomarkers. For example, genomic deletions on chromosome arm 18q are an indicator of colorectal carcinoma behavior and potentially...
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