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The order of genetic events associated with colorectal cancer progression inferred from meta‐analysis of copy number changes

6 Sept 2005

Abstract excerpt

To identify chromosomal aberrations that differentiate among the Dukes' stages of colorectal cancer (CRC) as well as those that are responsible for the progression into liver metastases, we performed a meta-analysis of data obtained from 31 comparative genomic hybridization (CGH) studies comprising a total of 859 CRCs. Individual copy number profiles for 373 primary tumors and 102 liver metastases were recorded...

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PMID: 16145679
DOI: 10.1002/gcc.20261

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