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Article

Association of survival and disease progression with chromosomal instability: a genomic exploration of colorectal cancer.

Proceedings of the National Academy of Sciences of the United States of America - 28 Apr 2009

Sheffer Michal, Bacolod Manny D, Zuk Or, Giardina Sarah F, Pincas Hanna, Barany Francis, Paty Philip B, Gerald William L, Notterman Daniel A, Domany Eytan

Abstract excerpt

During disease progression the cells that comprise solid malignancies undergo significant changes in gene copy number and chromosome structure. Colorectal cancer provides an excellent model to study this process. To indentify and characterize chromosomal abnormalities in colorectal cancer, we per...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19359472
DOI: 10.1073/pnas.0902232106
PMCID: PMC2678450

Genes

AURKA
CCDC68
CSMD1
FGF23
FGF6
LYN
MET
MMP9
MYBL2
MYC
PMEPA1
PTEN
VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19359472-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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