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DNA copy number profiling reveals different patterns of chromosomal instability within colorectal cancer according to the age of onset

25 Mar 2015

Abstract excerpt

Chromosomal instability resulting in copy number alterations is a hallmark of colorectal cancer (CRC). However, few studies have attempted to characterize the chromosomal changes occurring in early-onset CRC in order to compare them with those taking place within the more extensively studied late-onset CRC subset. Our aim was to characterize the genomic profiles of these two groups of colorectal tumors and to...

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PMID: 25808986
DOI: 10.1002/mc.22315

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