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Article

Unraveling the directional link between adiposity and inflammation: a bidirectional Mendelian randomization approach.

The Journal of clinical endocrinology and metabolism - 1 Jan 2010

Welsh Paul, Polisecki Eliana, Robertson Michele, Jahn Sabine, Buckley Brendan M, de Craen Anton J M, Ford Ian, Jukema J Wouter, Macfarlane Peter W, Packard Chris J, Stott David J, Westendorp Rudi G J, Shepherd James, Hingorani Aroon D, Smith George Davey, Schaefer Ernst, Sattar Naveed

Abstract excerpt

CONTEXT: Associations between adiposity and circulating inflammation markers are assumed to be causal, although the direction of the relationship has not been proven. OBJECTIVE: The aim of the study was to explore the causal direction of the relationship between adiposity and inflammation using a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19906786
DOI: 10.1210/jc.2009-1064
PMCID: PMC2805500

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CRP
FTO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19906786-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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