Elucidation of causal direction between asthma and obesity: a bi-directional Mendelian randomization study

Abstract excerpt

BACKGROUND: Observational associations between asthma and obesity are well established, but inferring causality is challenging. We leveraged publicly available summary statistics to ascertain the causal direction between asthma and obesity via Mendelian randomization in European-ancestry adults. METHODS: We performed two-sample bi-directional Mendelian randomization analysis using publicly available genome-wide...

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