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Article

Mapping the causal associations of cytokines with sarcopenia and aging traits: Evidence from bidirectional Mendelian randomization.

Journal of cachexia, sarcopenia and muscle - 1 Jun 2024

Liu Mingchong, Fu Xiao, Yu Daqian, Li Meng, Pan Yutao, Yang Chensong, Sun Guixin

Abstract excerpt

BACKGROUND: Cytokines and growth factors may serve as a bridge in studying the causal relationships between inflammaging and sarcopenia due to their roles in inflammaging. In this study, we aim to explore the causal association of cytokines with sarcopenia and aging traits and further identify the significant inflammation factors. METHODS: Bidirectional Mendelian randomization (MR) analysis was used to identify...

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Identifiers

PMID: 38556722
DOI: 10.1002/jcsm.13456
PMCID: PMC11154762

Genes

IL16

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