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Article

Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk Factors

23 Feb 2015

Abstract excerpt

Observational studies have reported different effects of adiposity on cardiovascular risk factors across age and sex. Since cardiovascular risk factors are enriched in obese individuals, it has not been easy to dissect the effects of adiposity from those of other risk factors. We used a Mendelian randomization approach, applying a set of 32 genetic markers to estimate the causal effect of adiposity on blood...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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Share to Genetic Associations and Epidemiology

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PMID: 25712996
DOI: 10.2337/db14-0988

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