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Article

Comparative biochemical analysis of HIV-1 subtype B and C integrase enzymes.

Retrovirology - 11 Nov 2009

Bar-Magen Tamara, Sloan Richard D, Faltenbacher Verena H, Donahue Daniel A, Kuhl Björn D, Oliveira Maureen, Xu Hongtao, Wainberg Mark A

Abstract excerpt

BACKGROUND: Integrase inhibitors are currently being incorporated into highly active antiretroviral therapy (HAART). Due to high HIV variability, integrase inhibitor efficacy must be evaluated against a range of integrase enzymes from different subtypes. METHODS: This study compares the enzymatic...

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Identifiers

PMID: 19906306
DOI: 10.1186/1742-4690-6-103
PMCID: PMC2779801

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19906306-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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