Article
Structural differences between apolipoprotein E3 and E4 as measured by (19)F NMR.
Protein science : a publication of the Protein Society - 1 Jan 2010
Garai Kanchan, Mustafi Sourajit M, Baban Berevan, Frieden Carl
Abstract excerpt
The apolipoprotein E family contains three major isoforms (ApoE4, E3, and E2) that are directly involved with lipoprotein metabolism and cholesterol transport. ApoE3 and apoE4 differ in only a single amino acid with an arginine in apoE4 changed to a cysteine at position 112 in apoE3. Yet only apo...
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