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Article

Characterization of 5-HT3 receptor mutations identified in schizophrenic patients.

Journal of molecular neuroscience : MN - 1 Jan 2006

Thompson Andrew J, Sullivan Nora L, Lummis Sarah C R

Abstract excerpt

The 5-HT3 receptor is a member of the Cys-loop family of ligand-gated ion channels, proteins that have been implicated in the pathology of several neurological disorders. In this study, we examine two mutations (R344H and P391R) that have been previously identified in individuals diagnosed with schizophrenia. These mutations are located in the M3-M4 loop of the 5-HT3 receptor and their occurrence presents the...

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Source

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Identifiers

PMID: 17401153
DOI: 10.1385/JMN:30:3:273
PMCID: PMC2649375

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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