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Article

Induction by ionizing radiation of the gadd45 gene in cultured human cells: lack of mediation by protein kinase C.

1 Feb 1991

Abstract excerpt

The effect of ionizing radiation on the expression of two DNA-damage-inducible genes, designated gadd45 and gadd153, was examined in cultured human cells. These genes have previously been shown to be strongly and coordinately induced by UV radiation and alkylating agents in human and hamster cells. We found that the gadd45 but not the gadd153 gene is strongly induced by X rays in human cells. The level of gadd45...

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PMID: 1990262
DOI: 10.1128/mcb.11.2.1009

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Induction by ionizing radiation of the gadd45 gene in cultured human cells: lack of mediation by protein kinase C.PMID 1990262Read ↗

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