Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comprehensive search for X-ray-responsive elements and binding factors in the regulatory region of the GADD45a gene.

Journal of radiation research - 1 Dec 2003

Daino Kazuhiro, Ichimura Sachiko, Nenoi Mitsuru

Abstract excerpt

The growth arrest and DNA damage-inducible protein 45alpha (GADD45a) gene is responsive to a variety of DNA-damaging agents. It is known that induction of the GADD45a gene is regulated in a p53-dependent manner after ionizing irradiation. Our previous study showed that X-ray irradiation increased the transcription rate of the GADD45a gene much earlier than the maximum accumulation of stabilized p53 protein in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Damage
Share to Dose-Response Relationship, Radiation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kruppel-Like Factor 4

Share to Radiation, Ionizing

Share to Regulatory Sequences, Nucleic Acid

Share to Response Elements

Share to Ultraviolet Rays

Share to X-Rays

Source

Identifiers

PMID: 15031557
DOI: 10.1269/jrr.44.311

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comprehensive search for X-ray-responsive elements and binding factors in the regulatory region of the GADD45a gene.PMID 15031557Read ↗

Growth arrest and DNA damage-inducible 45: a new player on inflammatory diseasesSemantic proximity Read ↗

Induction by ionizing radiation of the gadd45 gene in cultured human cells: lack of mediation by protein kinase C.Semantic proximity Read ↗

BRCA1 regulates GADD45 through its interactions with the OCT-1 and CAAT motifs.Semantic proximity Read ↗

The stress-responsive gene GADD45G is a functional tumor suppressor, with its response to environmental stresses frequently disrupted epigenetically in multiple tumors.Semantic proximity Read ↗

Transcriptional regulation of IER5 in response to radiation in HepG2.Semantic proximity Read ↗

p53-Mediated DNA Repair Responses to UV Radiation: Studies of Mouse Cells Lacking p53, p21, and/orgadd45 GenesSemantic proximity Read ↗

Regulation of mouse GADD34 gene transcription after DNA damaging agent methylmethane sulfonate.Semantic proximity Read ↗

Growth Differentiation Factor-15 (GDF-15) is a potential marker of radiation response and radiation sensitivitySemantic proximity Read ↗

The role of D-GADD45 in oxidative, thermal and genotoxic stress resistance.Semantic proximity Read ↗

Tumor Suppressor p53 Can Participate in Transcriptional Induction of the <i>GADD45</i> Promoter in the Absence of Direct DNA BindingSemantic proximity Read ↗

The <i>gadd</i> and <i>MyD</i> Genes Define a Novel Set of Mammalian Genes Encoding Acidic Proteins That Synergistically Suppress Cell GrowthSemantic proximity Read ↗

Expression of the Drosophila melanogaster GADD45 homolog (CG11086) affects egg asymmetric development that is mediated by the c-Jun N-terminal kinase pathway.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.