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Article

Increased generation of fibrocytes in thyroid-associated ophthalmopathy.

The Journal of clinical endocrinology and metabolism - 1 Jan 2010

Douglas Raymond S, Afifiyan Nikoo F, Hwang Catherine J, Chong Kelvin, Haider Uzma, Richards Patrick, Gianoukakis Andrew G, Smith Terry J

Abstract excerpt

CONTEXT: The pathogenic basis for Graves' disease (GD) continues to elude our understanding. Specifically why activating antibodies are generated against self-antigens remains uncertain as does the identity of the antigen(s) that provokes orbital involvement in GD, a process known as thyroid-associated ophthalmopathy (TAO). OBJECTIVE: The aim of the study was to determine whether CD34(+) fibrocytes are generated...

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Source

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Identifiers

PMID: 19897675
DOI: 10.1210/jc.2009-1614
PMCID: PMC2805489

Genes

TSHR
CXCR4
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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