Article
Novel aspects of orbital fibroblast pathology.
Journal of endocrinological investigation - 1 Mar 2004
Smith T J
Abstract excerpt
Orbital fibroblasts exhibit a unique phenotype including exaggerated responses to proinflammatory cytokines. We hypothesize that the unusual susceptability of these fibroblasts to molecular cues underlies the involvement of the orbit in Graves' ophthalmopathy. A number of attributes of orbital fibroblasts are reviewed in this article. In addition, we have found IgG circulating in patients with Graves' disease...
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