Article

Immune-parenchymal multicellular niches are shared across distinct thyroid autoimmune diseases

2025-04-03

Abstract excerpt

<h4>ABSTRACT</h4> Thyroid hormone, produced in the thyroid gland, regulates metabolism, development, and cardiac function. The thyroid is susceptible to autoimmune attack by both cellular and humoral immunity exemplified by Hashimoto’s thyroiditis (HT) and Graves’ Disease (GD), respectively. In HT, immune-mediated destruction impairs thyroid hormone production, while in GD, stimulating autoantibodies promote over...

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Literature Corpus work: 7a860639-37e3-5a42-a2a9-bc51dbe34220
DOI: 10.1101/2025.03.30.646176

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