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Article

Can serotonin transporter genotype predict serotonergic function, chronicity, and severity of drinking?

Progress in neuro-psychopharmacology & biological psychiatry - 1 Jan 2008

Johnson Bankole A, Javors Martin A, Roache John D, Seneviratne Chamindi, Bergeson Susan E, Ait-Daoud Nassima, Dawes Michael A, Ma Jennie Z

Abstract excerpt

Serotonin transporter (5-HTT) activity is greater in carriers of the long (L) vs. short (S) alleles of the 5-HTT-linked polymorphic region (5'-HTTLPR) among healthy control subjects but not alcohol-dependent adults. In 198 alcoholics, we determined the relationship between current or lifetime drinking and platelet 5-HTT function and density among allelic variants of the 5'-HTTLPR. SS subjects were younger than...

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Identifiers

PMID: 17950969
DOI: 10.1016/j.pnpbp.2007.07.030
PMCID: PMC2270792

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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