Article
Serotonin transporter promoter polymorphism genotype is associated with behavioral disinhibition and negative affect in children of alcoholics.
Alcoholism, clinical and experimental research - 1 Jul 2001
Twitchell G R, Hanna G L, Cook E H, Stoltenberg S F, Fitzgerald And H E, Zucker R A
Abstract excerpt
BACKGROUND: Serotonergic (5-HT) dysfunction has been implicated in the etiology of both behavioral disinhibition (BD) and negative affect (NA). This work extends our previous finding of relationships between whole blood 5-HT and both BD and NA in pubescent, but not prepubescent, children of alcoholics and continues examination of a hypothesized role of 5-HT dysfunction in alcoholism risk. The long and short (L...
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