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Article

Can serotonin transporter genotype predict craving in alcoholism?

Alcoholism, clinical and experimental research - 1 Aug 2009

Ait-Daoud Nassima, Roache John D, Dawes Michael A, Liu Lei, Wang Xin-Qun, Javors Martin A, Seneviratne Chamindi, Johnson Bankole A

Abstract excerpt

BACKGROUND: We hypothesize that functional control of the serotonergic system is regulated in part by differential expression of the serotonin (5-HT) transporter (5-HTT). Alcohol-dependent individuals with the LL/LS genotype (L-carriers), compared with those with the SS genotype, have a lower 5-HT neurotransmission, which we hypothesize would be associated with higher craving for alcohol among L-carriers. We...

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Identifiers

PMID: 19426172
DOI: 10.1111/j.1530-0277.2009.00962.x
PMCID: PMC2747793

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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