Article
Platelet content of nitric oxide synthase 3 phosphorylated at Serine 1177 is associated with the functional response of platelets to aspirin.
PloS one - 1 Jan 2013
Modrego Javier, Azcona Luis, Martín-Palacios Naiara, Zamorano-León José J, Segura Antonio, Rodríguez Pablo, Guerra Reddy, Tamargo Juan, Macaya Carlos, López-Farré Antonio J
Abstract excerpt
OBJECTIVE: To analyse if platelet responsiveness to aspirin (ASA) may be associated with a different ability of platelets to generate nitric oxide (NO). PATIENTS/METHODS: Platelets were obtained from 50 patients with stable coronary ischemia and were divided into ASA-sensitive (n = 26) and ASA-re...
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