Article
Pharmacogenetics of the antiplatelet effect of aspirin.
Current pharmaceutical design - 1 Jan 2012
Würtz Morten, Kristensen Steen Dalby, Hvas Anne-Mette, Grove Erik Lerkevang
Abstract excerpt
The concept of "pharmacogenetics" addresses genetically determined variation in how individuals respond to drugs. Accordingly, specific genetic variants have been suggested as contributors to a reduced response to various antiplatelet drugs. Aspirin is a cornerstone in secondary cardiovascular prevention and has been thoroughly investigated. The efficacy of aspirin is well documented, although with considerable...
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