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Article

No replication of genetic association between candidate polymorphisms and Alzheimer's disease.

Neurobiology of aging - 1 Aug 2011

Cousin Emmanuelle, Macé Sandrine, Rocher Corinne, Dib Colette, Muzard Gaëlle, Hannequin Didier, Pradier Laurent, Deleuze Jean-François, Génin Emmanuelle, Brice Alexis, Campion Dominique

Abstract excerpt

Alzheimer's disease is a genetically complex disorder, for which new putative susceptibility genes are constantly proposed in the literature. We selected 16 candidate genes involved in biological pathways closely related to the pathology, and for which a genetic association with Alzheimer's disease was previously detected: ACE, BACE1, BDNF, ECE1, HSPG2, IDE, IL1a, IL6, IL10, MAPT, PLAU, PrnP, PSEN1, SORL1, TFCP2...

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Source

Identifiers

PMID: 19889475
DOI: 10.1016/j.neurobiolaging.2009.09.004

Genes

MAPT
SORL1
TFCP2
ACE
BACE1
BDNF
ECE1
HSPG2
IDE
PLAU
PSEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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