Article
No association of SORL1 SNPs with Alzheimer's disease.
Neuroscience letters - 1 Aug 2008
Minster Ryan L, DeKosky Steven T, Kamboh M Ilyas
Abstract excerpt
SORL1 is an element of the amyloid precursor protein processing pathway and is therefore a good candidate for affecting Alzheimer's disease (AD) risk. Indeed, there have been reports of associations between variation in SORL1 and AD risk. We examined six statistically significant single-nucleotide polymorphisms from the initial observation in a large Caucasian American case-controls cohort (1000 late-onset AD...
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